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Congenital afibrinogenemia
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Congenital afibrinogenemia : ウィキペディア英語版
Congenital afibrinogenemia

Congenital afibrinogenemia is a rare inherited blood disorder in which the blood does not clot normally due to a lack of or a malfunction involving fibrinogen, a protein necessary for coagulation.
Fibrinogen is also known as Factor I. Its lack is inherited in an autosomic recessive way. It can express itself with excessive bleeding since birth (bleeding from umbilical cord, easy bruising, bleeding after circumcision) 〔National Hemophilia foundation http://www.hemophilia.org/NHFWeb/MainPgs/MainNHF.aspx?menuid=184&contentid=44&rptname=bleeding 〕
== Diagnostic tests ==

When a problem of fibrinogen is suspected, the following tests can be ordered:
*PT
*PTT
*Fibrinogen level in blood (total and clottable)
*Reptilase time
*Thrombin time

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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